hrp0082p1-d2-255 | Thyroid (1) | ESPE2014

Usefulness of Second Screening Strategy for Congenital Hypothyroidism in LBW Neonates

Cavarzere Paolo , Popa Florina Ion , Vincenzi Monica , Camilot Marta , Teofoli Francesca , Morosato Lorella , Maines Evelina , Gaudino Rossella , Lauriola Silvana , Antoniazzi Franco

Background: Thyroid function in preterm infants is often altered for various reasons. LBW or VLBW newborns frequently present a particular form of congenital hypothyroidism (CH) characterized by low FT4 and delayed TSH elevation. The incidence of this disease is 1:250 for VLBW babies and 1:1589 for LBW newborns. In this condition, neonatal screening based solely on TSH can miss the diagnosis, therefore some screening programs have proposed to repeat the screening te...